Clik here to view.
Endogenous experimental glioma model, links between glioma stem cells and...
Glioblastomas (GBM) are the most malignant solid tumours (grade IV) of CNS. They are glial lineage neoplasias with a high proliferative and invasive capacity, reaching to occupy an entire lobe of the...
View ArticleClik here to view.
Vascular Endothelial Growth Factor: Adaptive changes in the...
Brain postnatal development is modulated by adaptation and experience. Experience-mediated changes increase neuronal activity leading to increased metabolic demands that involve adaptive changes...
View ArticleClik here to view.
Broad characterization of endogenous peptides in the tree shrew visual system
Endogenous neuropeptides, acting as neurotransmitters or hormones in the brain, carry out important functions including neural plasticity, metabolism and angiogenesis. Previous neuropeptide studies...
View ArticleClik here to view.
Vascular Endothelial Growth Factor and Other Angioglioneurins: Key Molecules...
Angioneurins are a family of molecules that include vascular growth factors such as VEGF, neurotrophins such as BDNF, IGF-I, and Erythropoietin, among others. They affect both neural and vascular...
View ArticleClik here to view.
Enriched and Deprived Sensory Experience Induces Structural Changes and...
During postnatal development, sensory experience modulates cortical development, inducing numerous changes in all of the components of the cortex. Most of the cortical changes thus induced occur during...
View ArticleClik here to view.
Angiogenic Signalling Pathways Altered in Gliomas: Selection Mechanisms for...
The angiogenesis process is a key event for glioma survival, malignancy and growth. The start of angiogenesis is mediated by a cascade of intratumoural events: alteration of the microvasculature...
View ArticleClik here to view.
Effect of intracortical vascular endothelial growth factor infusion and...
VEGF is the major angiogenic and vascular permeability factor in health and disease. Vascular development depends on function, and in sensory areas is experience-dependent. Our aim was to investigate,...
View ArticleClik here to view.
Experience Mediated Development of the Visual Cortex Vascularization
The brain is highly vascularised, containing a very intricate network of capillaries (nearly every brain cell is located within 20 μm of a capillary). The endothelial cells that form the brain...
View ArticleClik here to view.
VEGF reverts the cognitive impairment induced by a focal traumatic brain...
The role of VEGF in the nervous system is extensive; apart from its angiogenic effect, VEGF has been described as a neuroprotective, neurotrophic and neurogenic molecule. Similar effects have been...
View ArticleClik here to view.
Increased physical activity is not enough to recover astrocytic population...
Elimination of sensory inputs (deprivation) modifies the properties of the sensory cortex and serves as a model for studying plasticity during postnatal development. Many studies on the effects of...
View Article